HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → 3-isobutyl-N4-hydroxy-N1-isopropyl-3,5,5-trimethyl-2-piperazinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | Hydroxyl | HCID 157350 | — |
| Reactant | 3,5,5-Trimethyl-3-(2-methylpropyl)-1-(propan-2-yl)piperazin-2-one | HCID 13131216 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Product | 3-isobutyl-N4-hydroxy-N1-isopropyl-3,5,5-trimethyl-2-piperazinone | HCID 13131220 | — |
Reaction Steps
A hydroxyl radical may be substituted for hydrogen on the N4 atom of the diaza ring in a manner similar to that described immediately hereinabove, except that only one equivalent of m-chloroperbenzoic acid is used. Thus starting with 1 equiv of N1 -isopropyl-3,5,5,-trimethyl-3-isobutyl-2-piperazinone and 2 equivs of m-chloroperbenzoic acid, we obtain 3-isobutyl-N4 -hydroxy-N1 -isopropyl-3,5,5-trimethyl-2-piperazinone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04466916 |
| Source dataset | uspto-grants-1984_08 |
| ORD ID | ord-44cc1af24cb64414ad3721346698e83e |
| Source note | uspto-grants-1984_08 |