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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 358377Generated: October 30, 2026

Diisopropylethylamine → HCID 20448827, compound

https://huagongshe.com/reaction/358377

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant2-(Hydroxymethyl)cyclopentanoneHCID 11094575—
ReactantHCID 86739604HCID 86739604—
SolventDiethyl EtherHCID 3283—
ProductHCID 20448827HCID 20448827100.9%

Reaction Steps

In a similar way to Example 24, (1), 293 mg of crude 4(RS)-(tetrahydropyran-2-yloxy)-3(RS)-[3-(tetrahydropyran-2-yloxy)-trans-1-octenyl]-2(SR)-(methanesulfonyloxymethyl)cyclopentanone was prepared from 243 mg of 4(RS)-(tetrahydropyran-2-yloxy)-3(RS)-]3-(tetrahydropyran-2-yloxy)trans-1-octenyl]-2(SR)-(hydroxymethyl)cyclopentanone. The crude product was reacted with diisopropylethylamine in ether in a similar way to Example 24, (2) to give 239 mg of crude 4(RS)-(tetrahydropyran-2-yloxy)-3(RS)-[3-(tetrahydropyran-2-yloxy)trans-1-octenyl]-2-methylidenecyclopentanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04466980
Source datasetuspto-grants-1984_08
ORD IDord-ffd5c50e9e464a638b1e917c75a9e8a1
Source noteuspto-grants-1984_08