Formic Acid → HCID 178517978, compound

HRID 358401Notes

Reaction equation

HRID 358401 reaction equation
[C:1]1([NH:7][NH:8][C:9]([NH2:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:12](O)=O.S(=O)(=O)(O)O>O>[C:1]1([N:7]2[CH:12]=[N:11][C:9]([OH:10])=[N:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 284Formic AcidHCID 1118Sulfuric AcidHCID 61002Phenicarbazide

Product 1

HCID 178517978HCID 178517978, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

151 g of 1-phenyl semicarbazide, 135.3 g (2.5 mols) of 85% formic acid (technical) and 25 g (0.25 mol) of concentrated sulfuric acid were stirred for six hours at 95° to 100° C. The viscous mass obtained was diluted with 400 ml of water and cooled. The precipitate consisting of 1-phenyl-1,2,4-triazolone-3 was filtered off and washed neutral with water. Drying at 100° C. and 200 mbar gave 145.5 g=90.3% of the theory, of 1-phenyl-1,2,4-triazolone-3 having a melting point of 285° to 286° C. ##STR2##

Workup

  1. customThe viscous mass obtained
  2. temperaturecooled
  3. filtrationwas filtered off
  4. washwashed neutral with water
  5. customDrying at 100° C.
  6. custom200 mbar gave 145.5 g=90.3% of the theory

Sources & evidence

ORD record
ord-3c3c237d012e4669b0c27ad0f2f8d64f
Source dataset
uspto-grants-1984_08
Patent number
US04467098

Reaction notes

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