Thionyl Chloride → HCID 13131775, compound

HRID 358440Notes

Reaction equation

HRID 358440 reaction equation
[C:1]([O:4][C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][C:14]=1[O:15][C:16](=[O:18])[CH3:17])[NH:11][CH:10]=[C:9]([C:19](O)=[O:20])[C:8]2=[O:22])(=[O:3])[CH3:2].S(Cl)([Cl:25])=O>>[C:1]([O:4][C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][C:14]=1[O:15][C:16](=[O:18])[CH3:17])[NH:11][CH:10]=[C:9]([C:19]([Cl:25])=[O:20])[C:8]2=[O:22])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 13131774HCID 13131774, compound

Product 1

HCID 13131775HCID 13131775, compound

Procedure

6,7-Diacetoxy-1,4-dihydro-4-oxoquinoline-3-carboxylic acid (70 mg) was heated under reflux for 2 hours in thionyl chloride (2 mL), and then the solvent was evaporated. To the residue was added benzene (30 mL). Benzene was evaporated and the residue was vacuum dried to give 6,7-diacetoxy-1,4-dihydro-4-oxoquinoline-3-carbonyl chloride.

Workup

  1. customthe solvent was evaporated
  2. additionTo the residue was added benzene (30 mL)
  3. customBenzene was evaporated
  4. customdried

Sources & evidence

ORD record
ord-4a642743f69e4636afe81961a31aaef1
Source dataset
uspto-grants-1984_08
Patent number
US04468394

Reaction notes

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