Thionyl Chloride → HCID 20448118, compound

HRID 358443Notes

Reaction equation

HRID 358443 reaction equation
O[C:2]1[C:3](O)=[CH:4][C:5]2[S:10][CH:9]=[C:8]([C:11](O)=[O:12])[C:7](=[O:14])[C:6]=2[CH:15]=1.S(Cl)([Cl:19])=O>>[O:14]=[C:7]1[C:6]2=[CH:15][CH2:2][CH2:3][CH:4]=[C:5]2[S:10][CH:9]=[C:8]1[C:11]([Cl:19])=[O:12]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 20448114HCID 20448114, compound

Product 1

HCID 20448118HCID 20448118, compound

Procedure

6,7-Dihydroxy-4-oxo-4H-1-benzothiopyran-3-carboxylic acid (100 mg) was heated under reflux for 2 hours in thionyl chloride (5 mL), and then the thionyl chloride was distilled off. To the residue was added benzene (20 mL). Benzene was distilled off again and the residue was vacuum dried to give 6,7-dihydro-4-oxo-4H-1-benzothiopyran-3-carbonyl chloride.

Workup

  1. distillationthe thionyl chloride was distilled off
  2. additionTo the residue was added benzene (20 mL)
  3. distillationBenzene was distilled off again
  4. customdried

Sources & evidence

ORD record
ord-2404f10bfdb34dd4942e222d4324e37a
Source dataset
uspto-grants-1984_08
Patent number
US04468394

Reaction notes

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