HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 6,7-dihydroxy-2-oxo-2H-1-benzopyran-3-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6,7-Dihydroxycoumarin-3-carboxylic Acid | HCID 13989553 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 6,7-dihydroxy-2-oxo-2H-1-benzopyran-3-carbonyl chloride | HCID 21286787 | — |
Reaction Steps
A mixture of 6,7-dihydroxy-2-oxo-2H-1-benzopyran-3-carboxylic acid (110 mg), thionyl chloride (5 mL), and dimethylformamide (one drop) was stirred for 2 hours at room temperature. The excess thionyl chloride was distilled off in vacuo. Benzene (20 mL) was added, followed by vacuum distillation and vacuum drying, to yield 6,7-dihydroxy-2-oxo-2H-1-benzopyran-3-carbonyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04468394 |
| Source dataset | uspto-grants-1984_08 |
| ORD ID | ord-863a20bb54bf471d93e5e18abcfbc03b |
| Source note | uspto-grants-1984_08 |