HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 20448116, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 20448121 | HCID 20448121 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 20448116 | HCID 20448116 | — |
Reaction Steps
A mixture of 6,7-diacetoxy-1,2-dihydro-2-oxoquinoline-3-carboxylic acid (100 mg), thionyl chloride (70 μL), and dimethylformamide (one drop) was heated under reflux for 4.5 hours in 50 mL of benzene, and the solvent was distilled off. Benzene (30 mL) was added to the residue and the benzene was distilled off again, followed by vacuum drying, to yield 6,7-diacetoxy-1,2-dihydro-2-oxoquinoline-3-carbonyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04468394 |
| Source dataset | uspto-grants-1984_08 |
| ORD ID | ord-4ebc0e9f6fc4498cab6986ace868f293 |
| Source note | uspto-grants-1984_08 |