HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 20448122, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6,7-Diacetoxy-1-methyl-1,2-dihydro-2-oxoquinoline-3-carboxylic acid | HCID 20448120 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 20448122 | HCID 20448122 | — |
Reaction Steps
A mixture of 6,7-diacetoxy-1-methyl-1,2-dihydro-2-oxoquinoline-3-carboxylic acid (60 mg), thionyl chloride (40 μL), and dimethylformamide (one drop) was heated under reflux for 2 hours in 40 mL of benzene, and the solvent was distilled off. Benzene (30 mL) was added to the residue and the benzene was distilled off again, followed by vacuum drying, to yield 6,7-diacetoxy-1-methyl-1,2-dihydro-2-oxoquinoline-3-carbonyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04468394 |
| Source dataset | uspto-grants-1984_08 |
| ORD ID | ord-742cf43dac6845fea55d7652e32d5573 |
| Source note | uspto-grants-1984_08 |