4-Chlorobenzenesulfonyl chloride → HCID 20066983, compound

Participants

Reaction Steps

A solution of 9-aminononanenitrile (2.0 g) in pyridine (60 ml) was treated with 4-chlorobenzenesulphonyl chloride (2.74 g) in portions. The solution was stirred for 18 hours then the solvent was removed in vacuo. The residue was dissolved in dilute hydrochloric acid and extracted with chloroform. The chloroform extract was dried over magnesium sulphate, the solvent was removed and the residue was chromatographed on silica gel eluted with chloroform to give the title compound (0.7 g) as a low melting solid.

Provenance & Evidence