HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl (Z)-7-phthalimidohept-5-enoate → (Z)-7-Phthalimidohept-5-enoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl (Z)-7-phthalimidohept-5-enoate | HCID 86744641 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Water | HCID 962 | — |
| Product | (Z)-7-Phthalimidohept-5-enoic Acid | HCID 67946768 | 80.9% |
Reaction Steps
A solution of methyl (Z)-7-phthalimidohept-5-enoate (1.56 g) in acetone (30 ml), concentrated hydrochloric acid (15 ml) and water (15 ml) was refluxed for 2.5 hours. Water (180 ml) was added and the solution was cooled. The precipitate was collected by filtration to give the title compound (1.2 g). m.p. 86°-88° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04997847 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-2b262f54b69b4c24a4ef5f86f10f6fce |
| Source note | uspto-grants-1991_03 |