4-Nitrobenzenesulfonyl chloride → HCID 20066984, compound

HRID 358632Notes

Reaction equation

HRID 358632 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([OH:11])=[O:10].[N+:12]([C:15]1[CH:20]=[CH:19][C:18]([S:21](Cl)(=[O:23])=[O:22])=[CH:17][CH:16]=1)([O-:14])=[O:13]>[OH-].[Na+]>[N+:12]([C:15]1[CH:16]=[CH:17][C:18]([S:21]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([OH:11])=[O:10])(=[O:23])=[O:22])=[CH:19][CH:20]=1)([O-:14])=[O:13]

Participants

4

Reactant 2

HCID 74044-Nitrobenzenesulfonyl chlorideHCID 660858-Aminooctanoic acid

Product 1

HCID 20066984HCID 20066984, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

A solution of 8-aminooctanoic acid in 10% sodium hydroxide solution was treated with 4-nitrobenzenesulphonyl chloride in the manner of Example 2 to give the title compound which, on recrystallisation from aqueous ethanol, had a melting point of 126°-7° C.

Sources & evidence

ORD record
ord-c616188fe71841a9a99962f8f7b933b0
Source dataset
uspto-grants-1991_03
Patent number
US04997847

Reaction notes

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