p-Bromobenzenesulfonyl chloride → HCID 20066944, compound

HRID 358633Notes

Reaction equation

HRID 358633 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([OH:11])=[O:10].[Br:12][C:13]1[CH:18]=[CH:17][C:16]([S:19](Cl)(=[O:21])=[O:20])=[CH:15][CH:14]=1>[OH-].[Na+]>[Br:12][C:13]1[CH:18]=[CH:17][C:16]([S:19]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([OH:11])=[O:10])(=[O:21])=[O:20])=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 7396p-Bromobenzenesulfonyl chlorideHCID 660858-Aminooctanoic acid

Product 1

HCID 20066944HCID 20066944, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

A solution of 8-aminooctanoic acid in 10% sodium hydroxide solution was treated with 4-bromobenzenesulphonyl chloride in the manner of Example 2 to give the title compound which, on recrystallisation from aqueous ethanol, had a melting point of 115°-116° C.

Sources & evidence

ORD record
ord-327ec32be8cb4435bcf7aa5249028978
Source dataset
uspto-grants-1991_03
Patent number
US04997847

Reaction notes

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