8-Aminooctanoic acid → HCID 20066961, compound

HRID 358646Notes

Reaction equation

HRID 358646 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([OH:11])=[O:10].[Cl:12][C:13]1[S:17][C:16]([S:18](Cl)(=[O:20])=[O:19])=[CH:15][CH:14]=1>>[Cl:12][C:13]1[S:17][C:16]([S:18]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([OH:11])=[O:10])(=[O:20])=[O:19])=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 660858-Aminooctanoic acidHCID 27339255-Chlorothiophene-2-sulfonyl chloride

Product 1

HCID 20066961HCID 20066961, compound

Procedure

8-Aminocaprylic acid (1.0 g, 0.006 mole) was treated with 5-chloro-2-thiophene sulphonyl chloride (1.37 g, 0.0063 mole) according to the method described in Example 4 to give the title compound after recrystallisation from isopropanol/water (1.39 g, m.p. 108°-9° C.).

Sources & evidence

ORD record
ord-935f333e4ae34cbaad68fb6980a0c084
Source dataset
uspto-grants-1991_03
Patent number
US04997847

Reaction notes

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