Sodium Hydroxide → 7-(4-Chlorophenylsulphonamido)-2,2-dimethylheptanoic Acid

HRID 358650Notes

Reaction equation

HRID 358650 reaction equation
C([O:3][C:4](=[O:24])[C:5]([CH3:23])([CH3:22])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][NH:11][S:12]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=1)(=[O:14])=[O:13])C.[OH-].[Na+]>>[Cl:21][C:18]1[CH:17]=[CH:16][C:15]([S:12]([NH:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][C:5]([CH3:23])([CH3:22])[C:4]([OH:24])=[O:3])(=[O:13])=[O:14])=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 20066981Ethyl-7-(4-chlorophenylsulphonamido)-2,2-dimethylheptanoate

Product 1

HCID 200669757-(4-Chlorophenylsulphonamido)-2,2-dimethylheptanoic AcidYield 6.1%

Procedure

Ethyl-7-(4-chlorophenylsulphonamido)-2,2-dimethylheptanoate (3.5 g, 0.09 mol) was treated with sodium hydroxide by the method described in Example 5(iii) to give the title compound (1.9 g) m.p. 132°-3° C. (dichloroethane/40°-60° petroleum ether).

Sources & evidence

ORD record
ord-dff64e4fa3e942e6947bcf2bdd5f997f
Source dataset
uspto-grants-1991_03
Patent number
US04997847

Reaction notes

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