HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 70045154, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-[(2S)-1-[3-(N-benzyl-N-methylcarbamoyl)propanoyl]pyrrolidin-2-yl]-2-oxoacetic acid ethyl ester | HCID 15660922 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 70045154 | HCID 70045154 | 150.4% |
Reaction Steps
A mixture of 2-[(2S)-1-[3-(N-benzyl-N-methylcarbamoyl) propanoyl]pyrrolidin-2-yl]-2-oxoacetic acid ethyl ester (626 mg), potassium carbonate (277 mg), methanol (7 ml) and water (4 ml) was stirred for 1 hr. at room temperature. Water was added to the reaction solution. The mixture was extracted with EtOAc. The extract was washed, dried and evaporated to give the title compound (458 mg) having the following physical data:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05411974 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-4f9439d06f60417e9df04a9770f7efe0 |
| Source note | uspto-grants-1995_05 |