HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl chloroformate → Methyl 4-[6-(butoxycarbonyl)amino-2,3,5-trimethylindol-1-ylmethyl]-3-methoxybenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl chloroformate | HCID 61140 | — |
| Reactant | Methyl 4-(6-amino-2,3,5-trimethylindol-1-ylmethyl)-3-methoxybenzoate | HCID 19744303 | — |
| Product | Methyl 4-[6-(butoxycarbonyl)amino-2,3,5-trimethylindol-1-ylmethyl]-3-methoxybenzoate | HCID 53990328 | 99% |
Reaction Steps
Similarly, starting from methyl 4-(6-amino-2,3,5-trimethylindol-1-ylmethyl)-3-methoxybenzoate and butyl chloroformate, methyl 4-[6-(butoxycarbonyl)amino-2,3,5-trimethylindol-1-ylmethyl]-3-methoxybenzoate (Example 39) was obtained in 99% yield as a white solid; partial NMR: 0.9 (t, 3H, CH2CH3), 1.3 (m,2H,CH2CH3), 1.5 (m,2H, CH2OCH2 0), 4.1 (t,2H,CH2O), 4.1 (t,2H,CH2O).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04997844 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-18d16db2602446aa85fbfd13c71764cd |
| Source note | uspto-grants-1991_03 |