Acetic Anhydride → HCID 53701521, compound

HRID 358853Notes

Reaction equation

HRID 358853 reaction equation
[CH2:1]([O:3][CH2:4][C:5]1[N:10]=[C:9]([C:11]([OH:13])=O)[C:8]([C:14]([OH:16])=[O:15])=[CH:7][CH:6]=1)[CH3:2].C(COC)OC.C(OC(=O)C)(=O)C>N1C=CC=CC=1>[CH2:1]([O:3][CH2:4][C:5]1[N:10]=[C:9]2[C:11]([O:16][C:14](=[O:15])[C:8]2=[CH:7][CH:6]=1)=[O:13])[CH3:2]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 80711,2-DimethoxyethaneHCID 20067185HCID 20067185, compound

Product 1

HCID 53701521HCID 53701521, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

21 g of 6-ethoxymethylpyridine-2,3-dicarboxylic acid are added to a mixture of 100 ml of dimethoxyethane, 28 ml of acetic anhydride and 15 ml of pyridine while stirring and the whole is further stirred for 6 hours at room temperature before being concentrated by evaporation under a high vacuum. 20 g of anhydride remain in the form of an oily liquid with a refractive index nD22 of 1.5480.

Workup

  1. stirringthe whole is further stirred for 6 hours at room temperature
  2. concentrationbefore being concentrated by evaporation under a high vacuum

Sources & evidence

ORD record
ord-abea89bfbf274a9da1aaa4f1a88a3ad7
Source dataset
uspto-grants-1991_03
Patent number
US04997947

Reaction notes

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