HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3H-Imidazo[4,5-c]pyridine-4-carboxylic acid, 4,5,6,7-tetrahydro-, methyl ester, hydrochloride (1:2)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3H,4H,5H,6H,7H-imidazo[4,5-c]pyridine-4-carboxylic acid dihydrochloride | HCID 67945944 | — |
| Product | 3H-Imidazo[4,5-c]pyridine-4-carboxylic acid, 4,5,6,7-tetrahydro-, methyl ester, hydrochloride (1:2) | HCID 67946063 | — |
Reaction Steps
32.3 g (0.134 moles) of 4,5,6,7-tetrahydroimidazo[4,5-c]pyridine-4-carboxylic acid dihydrochloride in 500 ml of methanol were treated below -5° C. with 16 ml (0.220 moles) of SOCl2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04999359 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-fa449267843049aa83d815c58283bb92 |
| Source note | uspto-grants-1991_03 |