HCID 54120432, compound → HCID 23365300, compound

Participants

Reaction Steps

A mixture of 6-[-2-(4-cyanophenyl)-3-(1,2,4-triazol- 1-yl)prop-1-enyl]nicotinonitrile (0.2 g) and 10% by weight palladium-on-carbon (0.1 g) in ethyl acetate (20 ml) was stirred rapidly under an atmosphere of hydrogen at atmospheric pressure for 1 h. The mixture was filtered and the filtrate was evaporated to dryness. The residue was triturated with diethyl ether to give a white solid, which was filtered off, washed with more ether (10 ml) and dried to give 6-[-2-(4-cyanophenyl)-3-(1,2,4-triazol-1-yl)propyl]nicotinonitrile, m.p. 98°.

Provenance & Evidence