Dimethyl Sulfoxide → HCID 67820121, compound

Participants

Reaction Conditions

Reaction Steps

5 g (0.011 mol) of 3-bromo-3,4-dihydro-2,2-dimethyl-7-methoxy-6-(p-tolylsulfonyl)-2H-benzo [b]pyran-4ol are dissolved in 32 ml of dimethyl sulfoxide, 4.9 g of valerolactam (0.0526 mol) and 0.8 g (0.033 mol) of NaH, 80 % suspension in oil, are added and the mixture is stirred for 5 hours at 40° C., poured on ice water and filtered with suction. The residue is boiled up several times with methanol. White crystals of melting point 261-63° C.

Provenance & Evidence