Dimethyl Sulfoxide → HCID 67820243, compound

Participants

Reaction Steps

0.75 g (0.025 mol) of 80 % NaH is introduced into 8.2 g (0.02 mol) of 3-bromo-3,4-dihydro-2,2-dimethyl-6-(4'-methyl-phenylsulfonyl)-2H-benzo[b]pyran -4-ol in 30 ml of dimethyl of dimethyl sulfoxide. After stirring for one hour at 20°, a further 0.75 g (0.025 mol) of 80 % NaH and 1.9 ml (0.025 mol) of 2-pyrrolidone are added and the mixture is stirred for 45 minutes at 40° and for 6 hours at 20°. After the mixture has been introduced into ice water, the precipitate is filtered off with suction, dried and recrystallized several times from methanol. Crystals of melting point: 242-243°.

Provenance & Evidence