HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 53925914, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | HCID 67934865 | HCID 67934865 | — |
| Product | HCID 53925914 | HCID 53925914 | — |
Reaction Steps
1 mol of 6-methyl-4-azasaccharine is suspended in 10 times the volume of methanol and heated at 100° C. with 1/10 molar equivalent of concentrated sulfuric acid in a bomb tube. After 18 hours the batch is concentrated by evaporation and the residue is washed with CHCl3 /NaHCO3 to give 3-(aminosulfonyl)-5-methylpyridine-2-carboxylic acid methyl ester in the form of a beige powder having a melting point of 86°-88° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04999426 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-422a9c6861024d99a00855c4293a5c0d |
| Source note | uspto-grants-1991_03 |