HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfate → Ethyl 3-methyl-3H-naphtho[2,3-e]indole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | HCID 20065895 | HCID 20065895 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | Ethyl 3-methyl-3H-naphtho[2,3-e]indole-2-carboxylate | HCID 20065894 | 97% |
Reaction Steps
Using the procedure described in Example 34A except that dimethyl sulfate was used as the alkylating agent, ethyl 3H-naphth[2,3-e]indole-2-carboxylate (H.G. Pars Pharmaceutical Laboratories, Inc.) gave a 97% yield of ethyl 3-methyl-3H-naphth[2,3-e]indole-2-carboxylate, mp 141°-144°, (EtOAc/hexane), (C,H,N).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04999369 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-2663904bb0504f58a8dace3bbcfadf94 |
| Source note | uspto-grants-1991_03 |