HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfate → ethyl 1-methyl-1H-naphth[2,3-g]indole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | ethyl 1H-naphth[2,3-g]indole-2-carboxylate | HCID 20065844 | — |
| Solvent | Methylenechloride Hexane | HCID 21226440 | — |
| Product | ethyl 1-methyl-1H-naphth[2,3-g]indole-2-carboxylate | HCID 20065877 | 96.2% |
Reaction Steps
Using the procedure outlined in Example 34A except that dimethyl sulfate was used as the alkylating agent, ethyl 1H-naphth[2,3-g]indole-2-carboxylate (H.G. Pars Pharmaceutical Laboratories, Inc.) gave a 96.2% yield of ethyl 1-methyl-1H-naphth[2,3-g]indole-2-carboxylate, mp 165°-165.5°, (CH2Cl2 /hexane), (C,H,N).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04999369 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-5a0c7cd76e8745c5a884f1b4b6a8b5b3 |
| Source note | uspto-grants-1991_03 |