Toluene → HCID 53766389, compound

Participants

Reaction Steps

By the procedure of Example 15, 4.29 g (0.04 mol) of N-methyl aniline was added to 75 ml of toluene containing 4.87 g (0.02 mol) of 2-chloro-4-trifluoromethyl-5-oxazolecarboxylate. The reaction mixture was stirred at reflux for 72 hours. The product mixture was slurried in ethyl ether, washed with water and 25% sulfuric acid, dried and concentrated. The residue was distilled and the distillate recrystallized from a chloroformmethylcyclohexane solution to yield 3.5 g of a white-powder product (m.p.=78°-81° C.) identified in Table I.

Provenance & Evidence