Sec-Butylamine → HCID 20064744, compound

Participants

Reaction Steps

By the procedure of Example 39, a stirred mixture of 20 ml acetonitrile, 3.65 g (49.8 mmol) of sec-butylamine, and 8 g (24.9 mmol) of benzyl 2-chloro-4-trifluoromethyl-5-thiazolecarboxylate (prepared as described in U.S. Pat. No. 4,199,506), was heated at reflux for 16 hours. The product was separated and then triturated in hexane to yield 2.70 g of an off-white solid product (m.p.=56°-57° C.) identified in Table I.

Provenance & Evidence