HuagongsheHuagongshe Chemistry Print Report · For research reference only
Anthranilamide → 2-[(4-Chlorobenzoyl)carbamothioylamino]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Anthranilamide | HCID 6942 | — |
| Reactant | 4-Chlorobenzoyl isothiocyanate | HCID 232162 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-[(4-Chlorobenzoyl)carbamothioylamino]benzamide | HCID 667641 | 85.8% |
Reaction Steps
To a stirred mixture of 10.5 g of 4-chlorobenzoyl isothiocyanate in 100 ml of tetrahydrofuran was added a mixture of 6.8 g of 2-aminobenzamide in 200 ml of tetrahydrofuran. After stirring for 3 hours, the solid was collected, giving 14.3 g of the desired product as grey crystals, mp 204°-206° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05001157 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-80e2c73e4c754b4cbc641e83c94de97f |
| Source note | uspto-grants-1991_03 |