化工社化工社 化学情報印刷レポート · 研究参考用
4-Methylbenzoyl isothiocyanate → N-Methyl-2-[[[(4-methylbenzoyl)amino]thioxomethyl]amino]benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methylbenzoyl isothiocyanate | HCID 140139 | — |
| 反応物 | 2-Amino-N-methylbenzamide | HCID 308072 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | N-Methyl-2-[[[(4-methylbenzoyl)amino]thioxomethyl]amino]benzamide | HCID 15135524 | 98% |
反応手順
To a stirred mixture of 8.0 g of 2-amino-N-methylbenzamide and 200 ml of ether was added dropwise, a solution of 10 g of 4-methylbenzoyl isothiocyanate in 100 ml of ether over 1 hour. After stirring several hours, the solid was collected, giving 17.1 g of the desired product as white crystals, mp 198°-200° C. (dec.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05001157 |
| 出典データセット | uspto-grants-1991_03 |
| ORD ID | ord-b448cc2c16c54ef08c36ca5decd5d6f1 |
| 出典メモ | uspto-grants-1991_03 |