Methanol → HCID 10424430, compound

Participants

Reaction Steps

To a solution of 4a (13.7 g, 47.2 mmol) in 100 mL of methanol at 0°-5° C. was added NaBH4 (2.68 g, 70.9 mmol). The mixture was stirred for 1 hr, diluted with ether and H2O. The organic layer was washed with H2O and brine and dried (MgSO4). Removal of the volatiles in vacuo provided a quantitive yield of product which was taken forward without further purification.

Provenance & Evidence