Tetrabutylammonium Fluoride → HCID 88495884, compound

HRID 359570Notes

Reaction equation

HRID 359570 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH2:13][CH:12]([N:14]3[C:18](=[O:19])[C:17]4=[CH:20][CH:21]=[CH:22][CH:23]=[C:16]4[C:15]3=[O:24])[CH2:11][C:10]([CH3:26])([CH3:25])[C:9]=2/[CH:27]=[CH:28]/[C@@H:29]2[O:34][C:33](=[O:35])[CH2:32][C@@H:31]([O:36][Si](C(C)(C)C)(C3C=CC=CC=3)C3C=CC=CC=3)[CH2:30]2)=[CH:4][C:3]=1[CH3:54].[F-].C([N+](CCCC)(CCCC)CCCC)CCC>CC(O)=O>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH2:13][CH:12]([N:14]3[C:15](=[O:24])[C:16]4=[CH:23][CH:22]=[CH:21][CH:20]=[C:17]4[C:18]3=[O:19])[CH2:11][C:10]([CH3:25])([CH3:26])[C:9]=2/[CH:27]=[CH:28]/[C@@H:29]2[O:34][C:33](=[O:35])[CH2:32][C@@H:31]([OH:36])[CH2:30]2)=[CH:4][C:3]=1[CH3:54]

Participants

4

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 88495732HCID 88495732, compound

Product 1

HCID 88495884HCID 88495884, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

In a manner similar to Scheme VIII, 44 (0.15 gm) was treated with tetrabutylammonium fluoride and HOAc and provided, after purification with SiO2 using 1:1 hexanes:EtOAc as eluent, 68 mg of the solid product.

Workup

  1. customprovided
  2. customafter purification with SiO2 using 1:1 hexanes

Sources & evidence

ORD record
ord-b75b677c49df49bd8ba8daf569f03e9d
Source dataset
uspto-grants-1991_03
Patent number
US05001144

Reaction notes

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