HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,6,6-Tetramethyl-4-piperidone → 4-Hydroxy-2,2,6,6-tetramethylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,6,6-Tetramethyl-4-piperidone | HCID 13220 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Product | 4-Hydroxy-2,2,6,6-tetramethylpiperidine | HCID 75471 | 99% |
Reaction Steps
2,2,6,6-tetramethyl-4-piperidinol was prepared by the reduction of 2,2,6,6-tetramethyl-4-piperidone (Aldrich) with sodium borohydride. It was purified by recrystallization from ligroin (bp 65-90). It formed colorless needles with mp 130-131; the reported mp is 128-131 (Lutz et al 1962).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05001233 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-72274f163bb94a69b41432f733c2d63d |
| Source note | uspto-grants-1991_03 |