1-Naphthalenesulfonyl chloride → N-hydroxymaleimide 1-naphthalenesulfonate

HRID 359672Notes

Reaction equation

HRID 359672 reaction equation
[OH:1][N:2]1[C:6](=[O:7])[CH:5]=[CH:4][C:3]1=[O:8].[C:9]1([S:19](Cl)(=[O:21])=[O:20])[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][CH:10]=1>CC(C)=O>[OH:1][N:2]1[C:6](=[O:7])[CH:5]=[CH:4][C:3]1=[O:8].[C:9]1([S:19]([O-:21])(=[O:1])=[O:20])[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][CH:10]=1

Participants

4

Reactant 2

HCID 665601-Naphthalenesulfonyl chlorideHCID 785351-hydroxy-1H-pyrrole-2,5-dione

Product 1

HCID 86744683N-hydroxymaleimide 1-naphthalenesulfonateYield 135%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

120 ml of acetone was added to 5.7 g of N-hydroxymaleimide and 11.3 g of 1-naphthalenesulfonyl chloride and then the same procedure as that of Preparation Example 1 was repeated to obtain 10.9 g of N-hydroxymaleimide-1-naphthalenesulfonate.

Workup

  1. customthe same procedure as that of Preparation Example 1

Sources & evidence

ORD record
ord-844a59761d704f9a89b1c9e27d930a9d
Source dataset
uspto-grants-1991_03
Patent number
US05002853

Reaction notes

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