HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole-3-pyruvic acid → HCID 12457675, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole-3-pyruvic acid | HCID 803 | — |
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 12457675 | HCID 12457675 | 70% |
Reaction Steps
Following the same method as previously described, 1,0 g 3-indole-pyruvic acid were reacted with 1,5 ml DBU and 790 microliters ethylbromide. In this case the benzene solution appeared red orange. After flash chromatography purification the ethyl ester was obtained with a yield of about 70%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05002963 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-b950a389228e4d7da502945220a05509 |
| Source note | uspto-grants-1991_03 |