4-Methylmorpholine → HCID 57034745, compound

Participants

Reaction Steps

922 mg of 3-(2-amino-5-phenoxyphenyl)thio-3-(3-fluoro-4-methoxyphenyl)-2-hydroxypropionic acid [prepared as described in step (b) above] were subjected to ring closure in the same manner as described in Example 1(c) using 0.59 ml of diphenylphosphorylazide and 0.59 ml of N-methylmorpholine The product was then extracted and purified as described in Example 1(c), to give 432 mg of the title compound as a powder, melting at 246-247° C.

Provenance & Evidence