HCID 10319339, compound → HCID 10000532, compound

Participants

Reaction Steps

A solution of 6.71 g of (2S, 3S)-3-(2-amino-5- benzylphenyl)thio-2-hydroxy-3-(4-methoxyphenyl)propionic acid [prepared as described in step (b) above] dissolved in 400 ml of xylene was heated under reflux for 8 hours whilst stirring. At the end of this time, the mixture was cooled to room temperature and the crystals which precipitated were collected by filtration and washed with xylene and hexane to give 5.8 g of the title compound, melting at 200-202° C. (with decomposition).

Provenance & Evidence