Toluene → HCID 57264165, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 149 g of 3,6-dichloropyridazine, 268.4 g of 2-allylphenol, 152 g of potassium carbonate, 400 ml of N-methylpyrrolidone and 900 ml of toluene was heated at 140° C. for 30 hours, the resulting water of reaction being distilled off azeotropically. Working up similarly to Example la) gave 317 g (92%) of a partially crystalline product, which consisted of an isomer mixture of allyl-containing and propenyl-containing products. After the addition of methanol and filtration, 140 g of pure 3,6-bis-(2-propenylphenoxy)-pyridazine were obtained as colorless crystals of melting point 165°-168° C.; 1H-NMR: 1.80 (d, CH ), 5.70-5.90 (m, small amount of cis-isomer), 6.20-6.50 (m, 4H, olef.) 7.0-7.7 (m, 1OH, arom.).

Provenance & Evidence