HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → 3-(5-Bromopentyl)-5-methylisoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 3-(3-Bromopropyl)-5-methyl-1,2-oxazole | HCID 13316975 | — |
| Reactant | 3-(5-Hydroxypentyl)-5-methylisoxazole | HCID 13316977 | — |
| Product | 3-(5-Bromopentyl)-5-methylisoxazole | HCID 13316978 | 77% |
Reaction Steps
3-(5-Bromopentyl)-5-methylisoxazole [XXVII; R9 =CH3, Hal=Br] was prepared by reacting 3-(5-hydroxypentyl)-5-methylisoxazole with bromine and triphenylphosphine according to the procedure of part (f) above, and was obtained in 77% yield as an oil, b.p. 140°-150° C. (0.05 mm).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05002960 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-77f113479f3e4b20882fed419e735c2b |
| Source note | uspto-grants-1991_03 |