HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 20063999, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(6-bromohexyloxy)-N-(2-hydroxyethyl)benzamide | HCID 20064087 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 20063999 | HCID 20063999 | 95% |
Reaction Steps
To 100 g of 4-(6-bromohexyloxy)-N-(2-hydroxyethyl)benzamide was added dropwise 112 g (75 ml) of thionyl chloride over a 20 minute period. The mixture was stirred for 45 minutes and then diluted with several volumes of ether. A solid product separated which was collected and rinsed with ether to give 90 g of 2-[4-(6-bromohexyloxy)phenyl]-4,5-dihydro-oxazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05002960 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-4e52a1a72c1a4aff8e46ad4c08726396 |
| Source note | uspto-grants-1991_03 |