HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 5-{5-[2,6-Dimethyl-4-(4-oxazolyl)phenoxy]pentyl}-3-methylisoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 5-(5-Bromopentyl)-3-methylisoxazole | HCID 13544046 | — |
| Reactant | 4-(4-Oxazolyl)-2,6-dimethylphenol | HCID 20064123 | — |
| Product | 5-{5-[2,6-Dimethyl-4-(4-oxazolyl)phenoxy]pentyl}-3-methylisoxazole | HCID 20064088 | — |
| Product | Hexane isopropyl acetate | HCID 22034165 | — |
Reaction Steps
5-{5-[2,6-Dimethyl-4-(4-oxazolyl)phenoxy]pentyl}-3-methylisoxazole [XXIX; n=5, R1 and R2 =CH3 ], m.p. 47°-48° C. (pale yellow powder from isopropyl acetate/hexane) was prepared in 38% yield by reacting 4-(4-oxazoly)-2,6-dimethylphenol, m.p. 113°-115° C., with 5-(5-bromopentyl)-3-methylisoxazole according to the procedure of Example 9(c) but using potassium hydroxide in place of potassium carbonate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05002960 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-8a34e375d54a4debbfb9c8543af1dca8 |
| Source note | uspto-grants-1991_03 |