Chlorine → 1,3-Isobenzofurandione, 5-fluoro-

HRID 359919Notes

Reaction equation

HRID 359919 reaction equation
[F:1][C:2]1(F)[CH2:12][CH2:11][CH:5]2[C:6]([O:8][C:9](=[O:10])[CH:4]2[CH2:3]1)=[O:7].ClCl>>[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[O:10])[O:8][C:6](=[O:7])[C:5]2=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 24526ChlorineHCID 140082495,5-Difluorohexahydro-2-benzofuran-1,3-dione

Product 1

HCID 675721,3-Isobenzofurandione, 5-fluoro-Yield 80%

Procedure

The procedure of Example III was repeated except that the feed was 4,4-difluorohexahydrophthalic anhydride, the vapor temperature was 240° C., reaction temperature was 255° C., the organic rate was 0.5 grams/minute, and the chlorine rate was 183 ml/min. The product, 4-fluorophthalic anhydride, was produced in 80% yield and 90% purity.

Workup

  1. customwas 240° C.
  2. customreaction temperature
  3. customwas 255° C.

Sources & evidence

ORD record
ord-032b60dd621946d4a93f66b106cb3332
Source dataset
uspto-grants-1991_03
Patent number
US05003088

Reaction notes

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