Methanol → HCID 178423442, compound

HRID 359926Notes

Reaction equation

HRID 359926 reaction equation
CO[C:3]1[C:4](=O)[CH:5]=[CH:6][C:7]([CH3:10])=[CH:8][CH:9]=1.[NH2:12][C:13]([NH2:15])=[S:14].C[O-].[Na+].CO.CO>C(O)(=O)C>[SH:14][C:13]1[N:12]=[C:4]2[CH:5]=[CH:6][C:7]([CH3:10])=[CH:8][CH:9]=[C:3]2[N:15]=1

Participants

6

Reactant 4

HCID 887MethanolHCID 2723790ThioureaHCID 14356253HCID 14356253, compoundHCID 23694274Sodium methanolate methanol

Product 1

HCID 178423442HCID 178423442, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

165 g of 2-methoxy-5-methyl-2,4,6-cycloheptatrien-1-one and 84 g of thiourea were added to 255 g of 28% sodium methoxide/methanol solution and everything was stirred for 30 minutes at room temperature. Next, 60 ml of methanol was added, and then acetic acid was added until the pH value of the resulting solution became 5 or so. The crystals thus precipitated were separated by filtration, fully washed with methanol and then dried.

Workup

  1. customThe crystals thus precipitated
  2. customwere separated by filtration
  3. washfully washed with methanol
  4. customdried

Sources & evidence

ORD record
ord-603567671b364e7c8fa86d8e5c4c04fc
Source dataset
uspto-grants-1991_03
Patent number
US05003077

Reaction notes

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