Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloroform → 2-Methoxymethyl-5-ethyl-5-methyl-1,3-dioxane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | 2-Ethyl-2-methyl-1,3-propanediol | HCID 66169 | — |
| 반응물 | Methoxyacetaldehyde | HCID 91563 | — |
| 반응물 | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-Methoxymethyl-5-ethyl-5-methyl-1,3-dioxane | HCID 14597943 | 89% |
반응 단계
A mixture of 590 g (5 moles) of 2-ethyl-2-methyl1,3-propanediol, 479 g (5.5 moles) of 85% strength methoxyacetaldehyde and 500 ml of chloroform was heated with 10 g of pyridinium p-toluenesulfonate under a water separator until water no longer separated off. The remaining solution was deionized using a mixed-bed ion exchanger, the solvent was removed under reduced pressure and the residue was distilled. 774 g (89% yield) of 2-methoxymethyl-5-ethyl-5-methyl-1,3-dioxane of boiling point 58° C./1 mbar were obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05003089 |
| 출처 데이터셋 | uspto-grants-1991_03 |
| ORD ID | ord-3403804319c2480286773f5eb72da6c8 |
| 출처 메모 | uspto-grants-1991_03 |