Cyclohexane → HCID 14597945, compound

HRID 359947Notes

Reaction equation

HRID 359947 reaction equation
[CH3:1][O:2][CH2:3][C:4]([CH:9]([CH3:11])[CH3:10])([CH2:7]O)[CH2:5][OH:6].[CH3:12][O:13][CH2:14][CH:15]=[O:16].C1CCCCC1>O>[CH3:12][O:13][CH2:14][CH:15]1[O:6][CH2:5][C:4]([CH2:3][O:2][CH3:1])([CH:9]([CH3:11])[CH3:10])[CH2:7][O:16]1

Participants

5

Reactant 3

HCID 8078CyclohexaneHCID 91563MethoxyacetaldehydeHCID 14597952HCID 14597952, compound

Product 1

HCID 14597945HCID 14597945, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 486 g (3 moles) of 2-methoxymethyl-2-isopropyl-1,3-propanediol, 287 g (3.3 moles) of 85% strength methoxyacetaldehyde and 250 ml of cyclohexane was heated with 5 g of the ion exchanger Lewasorb AC 10 under a water separator until water no longer separated off. The ion exchanger was filtered off, the solvent was stripped off under reduced pressure and the residue was subjected to fractional distillation under reduced pressure. 543 g (83% yield) of 2,5-dimethoxymethyl-5-isopropyl-1,3-dioxane of boiling point 95° C./1 mbar obtained.

Workup

  1. customno longer separated off
  2. filtrationThe ion exchanger was filtered off
  3. distillationthe residue was subjected to fractional distillation under reduced pressure

Sources & evidence

ORD record
ord-c71ad08f71ca4cd6b01a10dacecee061
Source dataset
uspto-grants-1991_03
Patent number
US05003089

Reaction notes

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