HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Butylbenzylamine → N-Benzyl-N-butyl-N'-(3-chlorophenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Butylbenzylamine | HCID 75467 | — |
| Reactant | Phenyl hydrogen (3-chlorophenyl)carbonimidate | HCID 232110 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | N-Benzyl-N-butyl-N'-(3-chlorophenyl)urea | HCID 13733049 | — |
Reaction Steps
A solution of 1.46 g of phenyl N-(3-chlorophenyl)carbamate in 15 ml of tetrahydrofuran was added to a solution of 1.92 g of N-benzyl-n-butylamine in 20 ml of tetrahydrofuran and the mixture stirred under reflux for hours. The mixture was diluted with hexane and the precipitate collected by filtration. Recrystallization from pentane afforded 1-benzyl-1-(n-butyl)-3-(3-chlorophenyl)urea, m.p. 69°-70° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05003106 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-134d467bc59046bfb4e5e9554afd3518 |
| Source note | uspto-grants-1991_03 |