HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-{[Benzyl(butyl)carbamoyl]amino}benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 15137690 | HCID 15137690 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-{[Benzyl(butyl)carbamoyl]amino}benzoic acid | HCID 15137691 | — |
Reaction Steps
A solution of 5.30 g of 1-benzyl-1-(n-butyl)-3-(4-carboethoxyphenyl)urea in 100 ml of ethanol is treated with 25 ml of 1N aqueous sodium hydroxide, stirred under reflux for 16 hours, allowed to cool, acidified with 1N hydrochloric acid, and filtered. The solid is recrystallized from ethanol to yield 1-benzyl-1-(n-butyl)-3-(4-carboxyphenyl)urea as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05003106 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-fd42e05fe1e247549ba88a82b7ccfca8 |
| Source note | uspto-grants-1991_03 |