1-isocyanato-2,4-dimethylbenzene → HCID 15137698, compound

HRID 359984Notes

Reaction equation

HRID 359984 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[N:9]=[C:10]=[O:11].[CH2:12]([C:16]1[CH:21]=[CH:20][C:19]([CH2:22][NH:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][OH:30])=[CH:18][CH:17]=1)[CH2:13][CH2:14][CH3:15]>CCCCCC>[CH2:12]([C:16]1[CH:17]=[CH:18][C:19]([CH2:22][N:23]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][OH:30])[C:10]([NH:9][C:3]2[CH:4]=[CH:5][C:6]([CH3:8])=[CH:7][C:2]=2[CH3:1])=[O:11])=[CH:20][CH:21]=1)[CH2:13][CH2:14][CH3:15]

Participants

4

Reactant 2

HCID 52075851-isocyanato-2,4-dimethylbenzeneHCID 15137694HCID 15137694, compound

Product 1

HCID 15137698HCID 15137698, compoundYield 69%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent2×

Procedure

To a stirred solution of 1.46 g of 2,4-dimethylphenyl isocyanate in 100 ml of hexane was added a solution of 2.63 g of 6-[[(4-butylphenyl)methyl]amino]-1-hexanol (prepared as described in Example 489), in 500 ml of hexane. The mixture was stirred at room temperature for 2 hours. Evaporation gave a gum. The gum was purified by chromatography to yield 2.81 g of the desired product as a colorles gum.

Workup

  1. customEvaporation
  2. customgave a gum
  3. customThe gum was purified by chromatography

Sources & evidence

ORD record
ord-18bd0fe75c6d405b98f659a271ed2897
Source dataset
uspto-grants-1991_03
Patent number
US05003106

Reaction notes

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