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HRID36018

反应详情

EQUATION

反应方程式

HRID 36018 的结构方程式

REACTANTS

反应物

3
结构：CS
HCID878

Methanethiol

CH4S

结构：CCCCc1nc(SC)c(C(=O)OCC)[nH]1
HCID9859628

Ethyl 2-butyl-5-methylsulfanyl-3H-imidazole-4-carboxylate

C11H18N2O2S

结构：COC(=O)c1ccccc1-c1ccc(CBr)cc1
HCID11012181

Methyl 4'-(bromomethyl)[1,1'-biphenyl]-2-carboxylate

C15H13BrO2

PRODUCTS

生成物

1
结构：CCCCc1nc(SC)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2C(=O)OC)cc1
HCID21479063

未命名化合物

收率 69.3%

PROCEDURE

实验过程

The operation is carried out as in Example 5, starting with 0.6 g of ethyl 2-butyl-4-(methylthio)-1H-imidazole-5-carboxylate (prepared as indicated in Stages C and D of Preparation 1, replacing the ethanethiol with methanethiol), using 907 mg of methyl 4'-(bromomethyl)-(1,1'-biphenyl)-2 -carboxylate. After chromatography on silica (eluant: methylene chloride--ethyl acetate (97-3)), 0.8 g of the desired product is obtained.

WORKUP

后处理

  1. customprepared
  2. customas indicated in Stages C and D of Preparation 1