Benzenemethanamine, 3-chloro- → 3-[2-(2-Pyridyl)ethylamino]-6-Methyl-1-(3-chlorobenzylacetamido)-2-Pyrazinone
Reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][NH:9][C:10]1[C:11](=[O:21])[N:12](CC(O)=O)[C:13]([CH3:16])=[CH:14][N:15]=1.[Cl:22][C:23]1[CH:24]=[C:25]([CH:28]=[CH:29][CH:30]=1)[CH2:26]N>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][NH:9][C:10]1[C:11](=[O:21])[N:12]([NH:12][C:11](=[O:21])[CH2:10][CH2:26][C:25]2[CH:28]=[CH:29][CH:30]=[C:23]([Cl:22])[CH:24]=2)[C:13]([CH3:16])=[CH:14][N:15]=1Participants
3
Procedure
The title compound was prepared from 3-[2-(2-pyridyl)ethylamino]-6-methyl-1-carboxymethylpyrazinone and 3-chlorobenzylamine using the procedure of EXAMPLE V, Step F, mp 201°-207° C.: MS (FAB) 412 (M+1)+.
Sources & evidence
- ORD record
- ord-2dea408adc1946449964f0e76a74708c
- Source dataset
- uspto-grants-1999_02
- Patent number
- US05866573
Reaction notes
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