Water → HCID 23435624, compound

Participants

Reaction Steps

A solution of 1-(13-Tetradecenyl)-3,7-dimethylxanthine (2.00 g, 5.35 mmol), 4-methylmorpholine-N-oxide (2.72 mL, 60% wt in water, 15.8 mmol) and potassium osmate dihydrate (21 mg, 0.05 mmol) in acetone/water 3:1 (80 mL) was stirred for 16 hours. Water (100 mL) and sodium sulfite (1 g) were added and stirred for 1 hour. The reaction mixture was extracted with dichloromethane (3×100 mL) and the organic phase dried (magnesium sulfate) and evaporated to yield 2.10 g (96% yield) 1-(13,14-Dihydroxytetradecyl)-3,7-dimethylxanthine as a white solid.

Provenance & Evidence