tert-Butoxy bis(dimethylamino)methane → HCID 54409687, compound

Participants

Reaction Conditions

Reaction Steps

3-Chloro-6-methyl-2-methylthio-5-nitropyridine (D7) (1.35 g, 6.18 mmol) was treated with tert-butoxy-bis(dimethylamino)methane (1.26 ml, 7.41 mmol) and was heated to 100° C. with stirrng. After 0.5 h, the reaction mixture was allowed to cool and was triturated with petroleum ether (60-80) (15 ml). The resultant dark solid was then filtered off and dried in vacuo to give the title compound as a dark red solid (1.56 g, 92%).

Provenance & Evidence